The Potential for Next Generation Sequencing in Forensics

Nicola Oldroyd
R&D, Illumina, United Kingdom

Genetic analysis continues to transform forensic investigations, with each technology advance enabling scientists to extract more and more information from forensic samples. The latest tool is next-generation sequencing (NGS), which has significantly enhanced biological research since its introduction in the mid-2000s.
NGS is just beginning to be used in the Forensic Genomics laboratory, with early studies in standard tandem repeat (STR) typing, mitochondrial DNA analysis, and dense panels of single nucleotide polymorphisms (SNPs) offering a tantalizing view of its advantages in revealing Forensic DNA evidence from even the smallest, most fragile, and highly mixed samples.

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